Article
Association between a promoter variant in the monoamine oxidase A gene and schizophrenia.
Schizophrenia research - 1 May 2003
Jönsson Erik G, Norton Nadine, Forslund Kaj, Mattila-Evenden Marja, Rylander Gunnar, Asberg Marie, Owen Michael J, Sedvall Göran C
Abstract excerpt
Monoaminergic transmission has been implicated in the pathophysiology of schizophrenia. We investigated a putative functional promoter polymorphism in the monoamine oxidase A (MAOA) gene in schizophrenic patients (n=133) and control subjects (n=377). In men, there was an association between the less efficiently transcribed alleles and schizophrenia (chi(2)=4.01, df=1, p<0.05). In women, no significant differences...
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