Article
Association analysis of the functional monoamine oxidase A gene promoter polymorphism in psychiatric disorders.
American journal of medical genetics - 8 Mar 2001
Syagailo Y V, Stöber G, Grässle M, Reimer E, Knapp M, Jungkunz G, Okladnova O, Meyer J, Lesch K P
Abstract excerpt
Functional characterization studies revealed that transcriptional activity of the human monoamine oxidase A (MAOA) gene is modulated by a polymorphic repetitive sequence located approximately 1.2 kb upstream of the ATG codon. To investigate the possible influence of the allelic variants of the MAOA gene-linked polymorphic region (MAOA-LPR) on the genetic predisposition to psychiatric disorders, we have performed...
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