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Article

p11 expression in human bronchial epithelial cells is increased by nitric oxide in a cGMP-dependent pathway involving protein kinase G activation.

The Journal of biological chemistry - 30 Nov 2001

Pawliczak R, Cowan M J, Huang X, Nanavaty U B, Alsaaty S, Logun C, Shelhamer J H

Abstract excerpt

The effect of nitric oxide on p11 expression was studied in an immortalized human bronchial epithelial cell line (BEAS-2B cells). Three nitric oxide donors were used: spermine NONOate (SP), (+/-)-S-nitroso-N-acetylpenicillamine (SNAP), and S-nitrosoglutathione (SNOG). All three nitric oxide donors had similar effects resulting in dose-dependent and time-dependent accumulation of p11 protein and an increase of...

Topics

Alkaloids
Annexin A2
Bronchi
Calcium-Binding Proteins
Carbazoles
Cell Nucleus
Chloramphenicol O-Acetyltransferase
Cyclic GMP
Cyclic GMP-Dependent Protein Kinases
Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Enzyme Activation

Enzyme Inhibitors

Epithelial Cells

Genes, Dominant

Genes, Reporter

Genes, jun

Immunoblotting

Indoles

Source

Identifiers

PMID: 11571284
DOI: 10.1074/jbc.M104993200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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