Article
A family history of breast cancer will not predict female early onset breast cancer in a population-based setting.
BMC cancer - 23 Jul 2008
de Bock Geertruida H, Jacobi Catharina E, Seynaeve Caroline, Krol-Warmerdam Elly M M, Blom Jannet, van Asperen Christi J, Cornelisse Cees J, Klijn Jan G M, Devilee Peter, Tollenaar Rob A E M, Brekelmans Cecile T M, van Houwelingen Johannes C
Abstract excerpt
BACKGROUND: An increased risk of breast cancer for relatives of breast cancer patients has been demonstrated in many studies, and having a relative diagnosed with breast cancer at an early age is an indication for breast cancer screening. This indication has been derived from estimates based on data from cancer-prone families or from BRCA1/2 mutation families, and might be biased because BRCA1/2 mutations explain...
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