A family of genes required for maintenance of cell wall integrity and for the stress response in Saccharomyces cerevisiae.

doi:10.1073/pnas.94.25.13804

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Article

A family of genes required for maintenance of cell wall integrity and for the stress response in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 9 Dec 1997

Verna J, Lodder A, Lee K, Vagts A, Ballester R

Abstract excerpt

The PKC1-MPK1 pathway in yeast functions in the maintenance of cell wall integrity and in the stress response. We have identified a family of genes that are putative regulators of this pathway. WSC1, WSC2, and WSC3 encode predicted integral membrane proteins with a conserved cysteine motif and a WSC1-green fluorescence protein fusion protein localizes to the plasma membrane. Deletion of WSC results in phenotypes...

Topics

Amino Acid Sequence
Cell Wall
Cyclic AMP
Fungal Proteins
Gene Deletion
Genes, Fungal
Genes, ras
Hot Temperature
Intracellular Signaling Peptides and Proteins
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitogen-Activated Protein Kinases

Molecular Sequence Data

Multigene Family

Mutation

Phenotype

Protein Kinase C

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Source

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Identifiers

PMID: 9391108
DOI: 10.1073/pnas.94.25.13804
PMCID: PMC28388

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