Article
Skewed inhibitory receptors expression in a TAP2-deficient patient.
Immunology letters - 3 Apr 2003
Crespí Catalina, Rosa Julià M, Muñoz-Saa Iván, Pérez-Castellano M Teresa, Milà Joan, Matamoros Núria
Abstract excerpt
Most of patients suffering from HLA class I deficiency due to mutations in TAP genes show a significative increase of the peripheral minor Vdelta1+ subpopulation of gammadelta T cells. Surface expression of inhibitory receptors (IR) for HLA class I molecules have been mainly attributed to Vdelta2+ gammadelta T clones. In this study we have analysed the expression of these receptors in both subsets of gammadelta T...
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