Article
Genetic heterogeneity of autoimmune disorders in the nonobese diabetic mouse.
Scandinavian journal of immunology - 1 Mar 2003
Johansson A C M, Lindqvist A-K B, Johannesson M, Holmdahl R
Abstract excerpt
The nonobese diabetic mouse is highly susceptible not only to diabetes but to several autoimmune diseases, and one might suspect that these are controlled by a shared set of genes. However, based on various gene-segregation experiments, it seems that only a few loci are shared and that each disorder is influenced also by a unique set of genes.
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