Article
Fibrinogen gene promoter -455 A allele as a risk factor for lacunar stroke.
Stroke - 1 Apr 2003
Martiskainen M, Pohjasvaara T, Mikkelsson J, Mäntylä R, Kunnas T, Laippala P, Ilveskoski E, Kaste M, Karhunen P J, Erkinjuntti T
Abstract excerpt
BACKGROUND AND PURPOSE: Elevated fibrinogen levels are suggested to increase the risk of myocardial infarction and stroke. Carriers of the A allele of the fibrinogen -455G/A polymorphism have increased plasma fibrinogen levels. We studied the association of this polymorphism with stroke subtype in the Stroke Aging Memory (SAM) cohort. METHODS: The SAM cohort comprises 486 consecutive patients 55 to 85 years of...
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