Article
Βeta-fibrinogen gene promoter A -455 allele associated with poor longterm survival among 55-71 years old Caucasian women in Finnish stroke cohort.
BMC neurology - 22 Jun 2014
Martiskainen Mika, Oksala Niku, Pohjasvaara Tarja, Kaste Markku, Oksala Anni, Karhunen Pekka J, Erkinjuntti Timo
Abstract excerpt
BACKGROUND: Women die of stroke more often than men. After menopause, the incidence of ischemic stroke increases rapidly. Elevated fibrinogen levels and smoking have been associated with an increased risk of stroke. In gene-cluster haplotype analyses, the beta-fibrinogen (FGB) promoter -455 G/A polymorphic locus was most strongly associated with elevated plasma fibrinogen levels. We investigated whether the FGB...
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