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Article

Association between two functional fibrinogen-related polymorphisms and ischemic stroke: a case-control study.

Genetic testing and molecular biomarkers - 1 Nov 2013

Zhang Jingjing, Yu Lihua, Yin Yanying, Lu Qian, Lei Lei, Xiao Jing, Guo Jian, Zhao JingJing, Wang Yanan, He Guoqian, Xu Yanming, He Li

Abstract excerpt

OBJECTIVES: Currently, there is a debate regarding the roles of two functional fibrinogen-related variants (rs6050 and rs1800790) and ischemic stroke (IS). MATERIALS AND METHODS: A total of 1402 subjects (834 cases and 568 controls) were genotyped for single-nucleotide polymorphisms rs6050 and rs1800790 with the ligation detection reaction method. RESULTS: We found that the homozygous minor allele genotype (GG)...

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PMID: 23944290
DOI: 10.1089/gtmb.2013.0131

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