Article
Genetic variation in the promoter region of the beta-fibrinogen gene is associated with ischemic stroke in a Japanese population.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jun 1998
Nishiuma S, Kario K, Yakushijin K, Maeda M, Murai R, Matsuo T, Ikeda U, Shimada K, Matsuo M
Abstract excerpt
Evidence suggests that an allelic variation in the beta fibrinogen gene may confer an increased risk of coronary artery disease and stroke. The role of the beta fibrinogen gene polymorphism and fibrinogen levels in ischemic stroke has not been determined in Japanese, who are more prone to stroke...
Topics
- Age Factors
- Aged
- Aged, 80 and over
- Alleles
- Arteriosclerosis
- Brain Ischemia
- Cerebrovascular Disorders
- Deoxyribonucleases, Type II Site-Specific
- Family Health
- Female
- Fibrinogen
- Gene Frequency
- Genes
- Genetic Variation
- Genotype