Article
Genome-wide search in Finnish families with inflammatory bowel disease provides evidence for novel susceptibility loci.
European journal of human genetics : EJHG - 1 Feb 2003
Paavola-Sakki Paulina, Ollikainen Vesa, Heliö Tiina, Halme Leena, Turunen Ulla, Lahermo Päivi, Lappalainen Maarit, Färkkilä Martti, Kontula Kimmo
Abstract excerpt
Epidemiological and genetic linkage studies have indicated a strong genetic basis for development of inflammatory bowel disease (IBD) which was recently supported by discovery of the Crohn's disease (CD) susceptibility gene termed NOD2/CARD15. We carried out a genome-wide linkage study in Finnish IBD families, providing a particular advantage to map susceptibility genes for ulcerative colitis (UC) within a...
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