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Article

Occurrence of a putative ancient-like isomerase involved in histidine and tryptophan biosynthesis.

EMBO reports - 1 Mar 2003

Barona-Gómez Francisco, Hodgson David A

Abstract excerpt

We report the occurrence of an isomerase with a putative (betaalpha)(8)-barrel structure involved in both histidine and trypto-phan biosynthesis in Streptomyces coelicolor A3(2) and Mycobacterium tuberculosis HR37Rv. Deletion of a hisA homologue (SCO2050) putatively encoding N'-[(5'-phosphoribosyl)-formimino]-5 amino-imidazole-4-carboxamide ribonucleotide isomerase from the chromosome of S. coelicolor A3(2)...

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Identifiers

PMID: 12634849
DOI: 10.1038/sj.embor.embor771
PMCID: PMC1315899

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