Article
The bifunctional role of aconitase in Streptomyces viridochromogenes Tü494.
Environmental microbiology - 1 Dec 2012
Michta Ewelina, Schad Klaus, Blin Kai, Ort-Winklbauer Regina, Röttig Marc, Kohlbacher Oliver, Wohlleben Wolfgang, Schinko Eva, Mast Yvonne
Abstract excerpt
In many organisms, aconitases have dual functions; they serve as enzymes in the tricarboxylic acid cycle and as regulators of iron metabolism. In this study we defined the role of the aconitase AcnA in Streptomyces viridochromogenes Tü494, the producer of the herbicide phosphinothricyl-alanyl-alanine, also known as phosphinothricin tripeptide or bialaphos. A mutant in which the aconitase gene acnA was disrupted...
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