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Article

The actinomycin biosynthetic gene cluster of Streptomyces chrysomallus: a genetic hall of mirrors for synthesis of a molecule with mirror symmetry.

Journal of bacteriology - 1 May 2010

Keller Ullrich, Lang Manuel, Crnovcic Ivana, Pfennig Frank, Schauwecker Florian

Abstract excerpt

A gene cluster was identified which contains genes involved in the biosynthesis of actinomycin encompassing 50 kb of contiguous DNA on the chromosome of Streptomyces chrysomallus. It contains 28 genes with biosynthetic functions and is bordered on both sides by IS elements. Unprecedentedly, the cluster consists of two large inverted repeats of 11 and 13 genes, respectively, with four nonribosomal peptide...

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Identifiers

PMID: 20304989
DOI: 10.1128/JB.01526-09
PMCID: PMC2863554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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