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Article

Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2003

Liu Wanqing, Innocenti Federico, Chen Peixian, Das Soma, Cook Edwin H, Ratain Mark J

Abstract excerpt

PURPOSE: Epidermal growth factor receptor (EGFR) plays a critical role in signal transduction and is a target for a novel class of anticancer agents that aim to inhibit EGFR-mediated cancer cell growth. Previous studies have demonstrated a dinucleotide (CA)(n) repeat polymorphism in intron 1 of EGFR, ranging from 14 to 21 repeats, that has been suggested to regulate EGFR expression. The longer allele with 21...

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Identifiers

PMID: 12631599

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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