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Article

Analysis of the dinucleotide repeat polymorphism in the epidermal growth factor receptor (EGFR) gene in head and neck cancer patients.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jun 2005

Etienne-Grimaldi M-C, Pereira S, Magné N, Formento J-L, Francoual M, Fontana X, Demard F, Dassonville O, Poissonnet G, Santini J, Bensadoun R-J, Szepetowski P, Milano G

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor (EGFR) overexpression is associated with poor prognosis in head and neck cancer. The first intron of EGFR gene is polymorphic (9-23 CA repeats) and transcription declines when the number of repeats increases. PATIENTS AND METHODS: EGFR polymorphism (fluorescent genotyping) and expression (ligand-binding assay) were analyzed in tumors and normal tissues from 112...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15829495
DOI: 10.1093/annonc/mdi189

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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