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Article

A novel nonsense mutation in the melanocortin-4 receptor associated with obesity in a Spanish population.

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Mar 2003

Marti A, Corbalán M S, Forga L, Martinez J A, Hinney A, Hebebrand J

Abstract excerpt

BACKGROUND: In recent years, several groups have reported dominant inheritance of obesity conferred by missense, nonsense and frameshift mutations in the melanocortin 4 receptor gene (MC4R). Hence, MC4R is involved in the most common monogenic form of human obesity described so far. OBJECTIVES: In this context, we screened a Spanish population, composed of obese subjects and normal weight controls, for mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12629567
DOI: 10.1038/sj.ijo.0802244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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