DNA hypermethylation in papillary renal cell carcinoma

Abstract excerpt

What’s known on the subject? and What does the study add? Epigenetic alterations play an essential role during carcinogenesis, and earlier studies suggested that global histone modification levels are predictive for patients’ outcome in various tumour entities (e.g. prostate, lung, breast and kidney cancer). So far, only smaller studies on histone H3K9 acetylation in patients with papillary urothelial neoplasm of...

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