Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for the early onset of aberrant promoter methylation in urothelial carcinoma

25 Apr 2006

Abstract excerpt

There is evidence that carcinoma in situ (CIS) is the precursor of invasive urothelial carcinoma, a tumour characterized by frequent gene promoter methylation. The timing of altered DNA methylation is unknown in this pathway. Here we investigate gene methylation in 196 consecutive samples of normal urothelium, CIS, and tumours from 104 patients with both CIS and invasive urothelial carcinoma using quantitative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bladder and Urothelial Cancer Treatments
Share to Epigenetics and DNA Methylation
Share to Urinary and Genital Oncology Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16639696
DOI: 10.1002/path.1991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for the early onset of aberrant promoter methylation in urothelial carcinomaPMID 16639696Read ↗

DNA methylation alterations in urothelial carcinomaSemantic proximity Read ↗

DNA Methylation in Urothelial CarcinomaSemantic proximity Read ↗

Unique DNA Methylation Patterns Distinguish Noninvasive and Invasive Urothelial Cancers and Establish an Epigenetic Field Defect in Premalignant TissueSemantic proximity Read ↗

Interest of methylated genes as biomarkers in urothelial cell carcinomas of the urinary tractSemantic proximity Read ↗

Promoter Hypermethylation in Tumour Suppressor Genes Shows Association with Stage, Grade and Invasiveness of Bladder CancerSemantic proximity Read ↗

DNA HYPERMETHYLATION ON MULTIPLE CpG ISLANDS ASSOCIATED WITH INCREASED DNA METHYLTRANSFERASE DNMT1 PROTEIN EXPRESSION DURING MULTISTAGE UROTHELIAL CARCINOGENESISSemantic proximity Read ↗

Promoter Hypermethylation Is Associated With Tumor Location, Stage, and Subsequent Progression in Transitional Cell CarcinomaSemantic proximity Read ↗

Promoter Hypermethylation Identifies Progression Risk in Bladder CancerSemantic proximity Read ↗

Detection of bladder cancer in urine sediments by a hypermethylation panel of selected tumor suppressor genesSemantic proximity Read ↗

Hypermethylation of an E-cadherin (CDH1) promoter region in high grade transitional cell carcinoma of the bladder comprising carcinoma in situ.Semantic proximity Read ↗

Frequent hypermethylation of promoter region of <i>RASSF1A</i> in tumor tissues and voided urine of urinary bladder cancer patientsSemantic proximity Read ↗

Aberrant Promoter Methylation of Multiple Genes during Pathogenesis of Bladder CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.