Article
Association analysis of the HOPA12bp polymorphism in schizophrenia and manic depressive illness.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2003
Kirov George, Georgieva Ludmila, Nikolov Ivan, Zammit Stan, Jones Gaynor, Poriazova Nadezhda, Tolev Todor, Owen Richard, Jones Sue, Owen Michael J
Abstract excerpt
Variations in exon 42 of the HOPA (human opposite paired) gene have been associated with mental retardation, hypothyroidism and psychiatric disorders. We attempted to replicate the association with schizophrenia using 309 parent-offspring trios from Bulgaria and 367 unrelated cases and 368 blood donors from the UK. We also tested 125 bipolar trios from Bulgaria, 112 bipolar trios from the UK and a sample of 178...
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