Article
The genomic structure and developmental expression patterns of the human OPA-containing gene (HOPA).
Human genetics - 1 Jan 2000
Philibert R A, Winfield S L, Damschroder-Williams P, Tengstrom C, Martin B M, Ginns E I
Abstract excerpt
We determined the genomic organization of the human OPA-containing gene (HOPA) and characterized its developmental expression. The gene encoding HOPA, which contains a rare polymorphism tightly associated with non-specific mental retardation, is 25 kb in length and consists of 44 exons. A promoter scan analysis demonstrates two possible transcription initiation sites without TATA boxes upstream from the putative...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.