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Article

Deleterious genetic influence of CX3CR1 genotypes on HIV-1 disease progression.

Journal of acquired immune deficiency syndromes (1999) - 1 Mar 2003

Faure Sophie, Meyer Laurence, Genin Emmanuelle, Pellet Philippe, Debré Patrice, Théodorou Ioannis, Combadière Christophe

Abstract excerpt

We previously reported that patients homozygous for a specific mutation (M280) in the chemokine receptor CX3CR1 progressed to AIDS more rapidly than those with other genotypes. This deleterious effect would predict that a cohort of prevalent patients would be depleted in M280 carriers, because these patients would have disappeared before recruitment. This hypothesis is confirmed in this new study based on the...

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Identifiers

PMID: 12626895
DOI: 10.1097/00126334-200303010-00014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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