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Article

Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors.

Proceedings of the National Academy of Sciences of the United States of America - 18 Mar 2003

Maretto Silvia, Cordenonsi Michelangelo, Dupont Sirio, Braghetta Paola, Broccoli Vania, Hassan A Bassim, Volpin Dino, Bressan Giorgio M, Piccolo Stefano

Abstract excerpt

Wntbeta-catenin signaling plays key roles in several developmental and pathological processes. Domains of Wnt expression have been extensively investigated in the mouse, but the tissues receiving the signal remain largely unidentified. To define which cells respond to activated beta-catenin during mammalian development, we generated the beta-catenin-activated transgene driving expression of nuclear...

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Identifiers

PMID: 12626757
DOI: 10.1073/pnas.0434590100
PMCID: PMC152286

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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