Article
Resequencing Study Identifies Rare Renin-Angiotensin-Aldosterone System Variants Associated With Blood Pressure Salt-Sensitivity: The GenSalt Study.
American journal of hypertension - 1 May 2017
Kelly Tanika N, Li Changwei, Hixson James E, Gu Dongfeng, Rao Dabeeru C, Huang Jianfeng, Rice Treva K, Chen Jichun, Cao Jie, Li Jianxin, Anderson Christopher E, He Jiang
Abstract excerpt
BACKGROUND: The role of rare variants in blood pressure (BP) salt-sensitivity is unknown. We conducted a resequencing study of the renin-angiotensin-aldosterone system (RAAS) to identify rare variants associated with BP salt-sensitivity among participants of the Genetic Epidemiology Network of Salt-Sensitivity (GenSalt) study. METHODS: The GenSalt study was conducted among 1,906 participants who underwent a 7-day...
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