Article
N-acetyltransferase-2 gene polymorphism as a possible biomarker for prostate cancer in Japanese men.
International journal of urology : official journal of the Japanese Urological Association - 1 Mar 2003
Hamasaki Takashi, Inatomi Hisato, Katoh Takahiko, Aono Hisami, Ikuyama Toshihiro, Muratani Tetsuro, Matsumoto Tetsuro
Abstract excerpt
BACKGROUND: The purpose of this study was to determine the frequency of a polymorphism of the candidate metabolic enzyme N-acetyltransferase-2 (NAT2) in Japanese prostate cancer patients and Japanese non-cancer controls, in order to determine if an association exists between NAT2 genotype and the occurrence, clinical stage and grade of prostate cancer. METHODS: In the present case-control study, 111 patients with...
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