Article
NAT2 gene polymorphism as a possible marker for susceptibility to bladder cancer in Japanese.
International journal of urology : official journal of the Japanese Urological Association - 1 Sept 1999
Inatomi H, Katoh T, Kawamoto T, Matsumoto T
Abstract excerpt
BACKGROUND: N-acetyltransferase (NAT) is known to metabolize the carcinogen arylamine. The polymorphism of the NAT2 gene is an important determinant of individual susceptibility to bladder cancer. There are significant interethnic differences in NAT2 allele frequencies. The relationship between NAT2 genotypes and bladder cancer in a Japanese population was investigated. METHODS: A case control study on 85 bladder...
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