Article
Increased number of CCR5+ CD4 T cells among south Indian adults probably associated with the low frequency of X4 phenotype of HIV-1 in India.
The Indian journal of medical research - 1 Sept 2002
Ramalingam Sandeep, Kannangai Rajesh, Vijayakumar Theophilus S, Subramanian Swaminathan, Abraham Oriapadickal C, Rupali Priscilla, Jesudason Mary V, Sridharan Gopalan
Abstract excerpt
BACKGROUND & OBJECTIVE: The shift of the human immunodeficiency virus (HIV) from nonsyncytium inducing strains (NSI/R5) to syncytium inducing strains (SI/X4) seen in subtype B infections during progression to acquired immunodeficiency syndrome (AIDS) is less frequently reported in subtype C. NSI and SI strains differ in the co-receptor they utilize to infect a T-cell. We postulated that a larger pool of CD4 T...
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