Article
Molecular mechanisms underlying the development of hepatocellular carcinoma.
Seminars in oncology - 1 Oct 2001
Bergsland E K
Abstract excerpt
Hepatocellular carcinoma (HCC) is a disease that is extremely difficult to manage and is markedly increasing in incidence. Malignant transformation generally occurs in the setting of liver dysfunction related to a number of different diseases, including viral hepatitis, alcoholic liver disease, and aflatoxin exposure. Short of surgical or ablative approaches, no standard therapy exists for HCC and the prognosis...
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