Molecular mechanisms underlying the development of hepatocellular carcinoma.

doi:10.1016/s0093-7754(01)90145-9

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Article

Molecular mechanisms underlying the development of hepatocellular carcinoma.

Seminars in oncology - 1 Oct 2001

Bergsland E K

Abstract excerpt

Hepatocellular carcinoma (HCC) is a disease that is extremely difficult to manage and is markedly increasing in incidence. Malignant transformation generally occurs in the setting of liver dysfunction related to a number of different diseases, including viral hepatitis, alcoholic liver disease, a...

Topics

Animals
Carcinoma, Hepatocellular
Cell Transformation, Neoplastic
Cell Transformation, Viral
Chromosome Aberrations
Humans
Liver Neoplasms
Models, Animal
Mutation

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