Molecular pathogenesis of human hepatocellular carcinoma.

doi:10.1016/s0300-483x(02)00253-6

Article

Molecular pathogenesis of human hepatocellular carcinoma.

Toxicology - 27 Dec 2002

Wang Xin W, Hussain S Perwez, Huo Teh-Ia, Wu Chuan-Ging, Forgues Marshonna, Hofseth Lorne J, Brechot Christian, Harris Curtis C

Abstract excerpt

Primary hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. However, the viral-chemical etiology as well as molecular mechanisms of HCC pathogenesis remains largely unknown. Recent studies in our laboratory have identified several potential factors that may contribute...

Topics

Carcinoma, Hepatocellular
Genes, p53
Hepatitis, Viral, Human
Humans
Liver Neoplasms
Mutation

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