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Article

Genomic structure and inducible expression of the IL-22 receptor alpha chain in mice.

1 Mar 2003

Abstract excerpt

IL-22 is a newly identified member of the interferon/IL-10 family. In humans, IL-22 signals through a heteroduplex receptor consisting of IL-22R and CRF2-4/IL-10Rbeta. To investigate the physiological function of IL-22 and IL-22R, we isolated a cDNA encoding the mouse IL-22R, which has been a missing component of the functional receptor complex for mouse IL-22. Subsequently, we identified the genomic sequence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12618864
DOI: 10.1038/sj.gene.6363934

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