Signaling from the IL-2 receptor to the nucleus.

doi:10.1016/s1359-6101(97)00021-x

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Article

Signaling from the IL-2 receptor to the nucleus.

Cytokine & growth factor reviews - 1 Dec 1997

Lin J X, Leonard W J

Abstract excerpt

Interleukin-2 has pleiotropic actions on the immune system and plays a vital role in the modulation of immune responses. Our current understanding of IL-2 signaling has resulted from in vitro studies that have identified the signaling pathways activated by IL-2, including the Jak-STAT pathways, a...

Topics

Adaptor Proteins, Signal Transducing
Adaptor Proteins, Vesicular Transport
Animals
Cell Nucleus
Cloning, Molecular
Endosomal Sorting Complexes Required for Transport
Gene Expression Regulation
Humans
Mice
Phenotype
Phosphatidylinositol 3-Kinases
Phosphoproteins
Protein-Tyrosine Kinases
Proteins
Receptors, Interleukin-2
Shc Signaling Adaptor Proteins
Signal Transduction
Src Homology 2 Domain-Containing, Transforming Protein 1

Source

Open in PubMed

Identifiers

PMID: 9620644
DOI: 10.1016/s1359-6101(97)00021-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9620644-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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