Article
Structure-based design of AIDS drugs and the development of resistance.
Vox sanguinis - 1 Aug 2002
Wlodawer Alexander
Abstract excerpt
AIDS is a major worldwide epidemic spread primarily through contact with infected blood during sexual activity, drug injection, birth, and, rarely now, blood transfusion. More than a dozen drugs for the treatment of AIDS have been introduced in the last 15 years and the process leading to their development offers an excellent example of the progress made in the field of rational drug design. The principal targets...
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