Article

Design of novel HIV-1 protease inhibitors with favorable oral properties using a virtual screening and lead optimization approach

2024-02-01

Abstract excerpt

Acquired Immunodeficiency Syndrome (AIDS) is a chronic and potentially fatal transmissible disease caused by the Human Immunodeficiency Virus (HIV). Since its discovery in 1981, an estimated 85 million cases and 40 million AIDS related deaths have occurred worldwide. Among the two types of HIV, HIV-1 accounts for over 90% of reported cases. Throughout the years, multiple drugs have been approved for the treatment...

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Literature Corpus work: f9135514-0796-5849-abe7-aba17cc49f17
DOI: 10.21203/rs.3.rs-3905529/v1

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