Article
GATA-6 is involved in PPARgamma-mediated activation of differentiated phenotype in human vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2003
Abe Mitsuru, Hasegawa Koji, Wada Hiromichi, Morimoto Tatsuya, Yanazume Tetsuhiko, Kawamura Teruhisa, Hirai Maretoshi, Furukawa Yutaka, Kita Toru
Abstract excerpt
OBJECTIVE: Peroxisome proliferator-activated receptor-gamma (PPARgamma) is a member of the nuclear receptor superfamily involved in the growth and differentiation of many cell types. Although the activation of PPARgamma in human vascular smooth muscle cells (VSMCs) inhibits the growth of these cells, the precise mechanism of this effect is unknown. PPARgamma-mediated growth inhibition of VSMCs is associated with...
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