Roles of inositol 1,4,5-trisphosphate receptors in spinocerebellar ataxias.

doi:10.1016/j.neuint.2016.01.007

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Article

Roles of inositol 1,4,5-trisphosphate receptors in spinocerebellar ataxias.

Neurochemistry international - 1 Mar 2016

Tada Masayoshi, Nishizawa Masatoyo, Onodera Osamu

Abstract excerpt

Modulation of the intracellular calcium concentration is a ubiquitous signaling system involved in the control of numerous biological processes in a wide variety of cells. Inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs), which act as calcium release channels in the ER membrane, play a key ro...

Topics

Animals
Calcium Signaling
Humans
Inositol 1,4,5-Trisphosphate Receptors
Mutation
Spinocerebellar Ataxias

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