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Article

Roles of inositol 1,4,5-trisphosphate receptors in spinocerebellar ataxias.

Neurochemistry international - 1 Mar 2016

Tada Masayoshi, Nishizawa Masatoyo, Onodera Osamu

Abstract excerpt

Modulation of the intracellular calcium concentration is a ubiquitous signaling system involved in the control of numerous biological processes in a wide variety of cells. Inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs), which act as calcium release channels in the ER membrane, play a key role in the regulation of intracellular calcium concentration. IP3R type 1 (IP3R1) is the major neuronal IP3R isoform in...

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Identifiers

PMID: 26827887
DOI: 10.1016/j.neuint.2016.01.007

Genes

ITPR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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