Article
Understanding stroke risk phenotypes in pediatric patients with sickle cell disease and concurrent moyamoya arteriopathy: insights from 61 cases at a single institution.
Journal of neurosurgery. Pediatrics - 13 Mar 2026
Papadakis Joanna E, Archer Natasha M, Singh Nikita, Puglisi Emma N, Keusch Dylan S, Piwowarczyk Paulina, Weber Daniel S, Slingerland Anna L, Smith Edward R, Heeney Matthew M, Aldana Philipp R, See Alfred Pokmeng
Abstract excerpt
OBJECTIVE: Children with sickle cell disease (SCD) are at risk of developing cerebral vasculopathies, increasing the risk of stroke. While some vasculopathies are medically managed, surgical revascularization might be needed in patients who also have moyamoya arteriopathy (MMA). The aim of this study was to characterize stroke timing and phenotype between children with homozygous SCD (HbSS) alone and those with...
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