Article
Porcine SRY promoter is a target for steroidogenic factor 1.
Biology of reproduction - 1 Apr 2003
Pilon Nicolas, Daneau Isabelle, Paradis Veronique, Hamel Frédéric, Lussier Jacques G, Viger Robert S, Silversides David W
Abstract excerpt
To study the process of mammalian sex determination and in particular to further understand the mechanisms of transcriptional regulation of the SRY gene, we have isolated a 4.5-kilobase (kb) pig SRY 5' flanking sequence. To facilitate the in vitro analysis of these sequences, we have generated a porcine genital ridge (PGR) cell line (9E11) that expresses SRY as well as SOX9, steroidogenic factor-1 (SF-1), and...
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