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Nuclear-Cytoplasmic “Tug of War” During Cloning: Effects of Somatic Cell Nuclei on Culture Medium Preferences of Preimplantation Cloned Mouse Embryos1

1 Apr 2002

Abstract excerpt

Cloning by somatic cell nuclear transfer is critically dependent upon early events that occur immediately after nuclear transfer, and possibly additional events that occur in the cleaving embryo. Embryo culture conditions have not been optimized for cloned embryos, and the effects of culture conditions on these early events and the successful initiation of clonal development have not been examined. To evaluate...

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PMID: 11906939
DOI: 10.1095/biolreprod66.4.1178

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