Article
Association study of oestrogen receptor alpha gene polymorphism and suicidal behaviours in major depressive disorder.
Psychiatric genetics - 1 Mar 2003
Tsai Shih-Jen, Wang Ying-Chieh, Hong Chen-Jee, Chiu Hsien-Jane
Abstract excerpt
OBJECTIVE: Gender comparison in epidemiological studies has consistently demonstrated a greater prevalence for major depressive disorders (MDD) in females. Several lines of evidence have implicated oestrogen pathways in this gender difference. Furthermore, there is evidence that attempted suicides are more frequent in women. A population-based association study was used to test the hypothesis that the genetic...
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