Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relish-mediated immune deficiency in the transgenic mosquito Aedes aegypti.

Proceedings of the National Academy of Sciences of the United States of America - 4 Mar 2003

Shin Sang Woon, Kokoza Vladimir, Lobkov Iouri, Raikhel Alexander S

Abstract excerpt

The lack of genetic means has been a serious limitation in studying mosquito immunity. We generated Relish-mediated immune deficiency (RMID) by transforming Aedes aegypti with the Delta Rel transgene driven by the vitellogenin (Vg) promoter using the pBac[3xP3-EGFP, afm] vector. A stable transformed line had a single copy of the Vg-Delta Rel transgene. The Vg-Delta Rel transgene expression was highly activated by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aedes
Share to Blotting, Northern

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Defensins

Share to Enterobacter cloacae

Share to Gram-Negative Bacteria

Share to Insect Vectors

Share to Luminescent Proteins

Share to Transgenes

Source

Open in PubMed Open full text

Identifiers

PMID: 12594340
DOI: 10.1073/pnas.0537347100
PMCID: PMC151389

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relish-mediated immune deficiency in the transgenic mosquito Aedes aegypti.PMID 12594340Read ↗

Transgenesis and reverse genetics of mosquito innate immunity.Semantic proximity Read ↗

A Thioester-Containing Protein Controls Dengue Virus Infection in Aedes aegypti Through Modulating Immune ResponseSemantic proximity Read ↗

The RNA interference pathway affects midgut infection- and escape barriers for Sindbis virus in Aedes aegyptiSemantic proximity Read ↗

Caspar Controls Resistance to Plasmodium falciparum in Diverse Anopheline SpeciesSemantic proximity Read ↗

Engineered Aedes aegypti JAK/STAT Pathway-Mediated Immunity to Dengue VirusSemantic proximity Read ↗

Transglutaminase-catalyzed protein-protein cross-linking suppresses the activity of the NF-κB-like transcription factor relish.Semantic proximity Read ↗

C-Type Lectins Link Immunological and Reproductive Processes in Aedes aegyptiSemantic proximity Read ↗

Transgene‐mediated suppression of the RNA interference pathway in A edes aegypti interferes with gene silencing and enhances S indbis virus and dengue virus type 2 replicationSemantic proximity Read ↗

Engineering RNA interference-based resistance to dengue virus type 2 in genetically modified Aedes aegypti.Semantic proximity Read ↗

Activation of mosquito immunity blocks the development of transmission-stage filarial nematodesSemantic proximity Read ↗

Female-specific flightless phenotype for mosquito control.Semantic proximity Read ↗

Impact of Chronic Infection on Resistance and Tolerance to Secondary Infection in Drosophila melanogasterSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.