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Article

Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis?

Molecular and cellular biology - 1 Apr 1998

Lafontaine D L, Preiss T, Tollervey D

Abstract excerpt

One of the few rRNA modifications conserved between bacteria and eukaryotes is the base dimethylation present at the 3' end of the small subunit rRNA. In the yeast Saccharomyces cerevisiae, this modification is carried out by Dim1p. We previously reported that genetic depletion of Dim1p not only blocked this modification but also strongly inhibited the pre-rRNA processing steps that lead to the synthesis of 18S...

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Identifiers

PMID: 9528805
DOI: 10.1128/MCB.18.4.2360
PMCID: PMC121492

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Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis?PMID 9528805Read ↗

The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast.Semantic proximity Read ↗

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Rrp8p is a yeast nucleolar protein functionally linked to Gar1p and involved in pre-rRNA cleavage at site A2.Semantic proximity Read ↗

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