Article
Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis?
Molecular and cellular biology - 1 Apr 1998
Lafontaine D L, Preiss T, Tollervey D
Abstract excerpt
One of the few rRNA modifications conserved between bacteria and eukaryotes is the base dimethylation present at the 3' end of the small subunit rRNA. In the yeast Saccharomyces cerevisiae, this modification is carried out by Dim1p. We previously reported that genetic depletion of Dim1p not only...
Topics
- Alleles
- Aminoglycosides
- Anti-Bacterial Agents
- Cell Nucleolus
- Cell Nucleus
- Gene Expression Regulation, Enzymologic
- Genes, Lethal
- Methylation
- Methyltransferases
- Mutation
- Promoter Regions, Genetic
- Protein Biosynthesis
- RNA Processing, Post-Transcriptional
- RNA, Ribosomal, 18S
- Ribosomes
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription, Genetic