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Article

Interpretation of complex phenotypes: lessons from the Mitf gene.

Pigment cell & melanoma research - 1 Dec 2010

Steingrímsson Eiríkur

Abstract excerpt

SUMMARY: Mutations provide important structure–function relationships by allowing the correlation of phenotypes to the underlying genotypes. Knockout mutations that lead to loss-of-function are important and informative in this respect. However, spontaneous and induced mutations sometimes provide surprising phenotypes, which lead to unexpected functional insights and novel biochemical pathways, especially when...

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Identifiers

PMID: 21823251
DOI: 10.1111/j.1755-148x.2010.00769.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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