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Article

Nodal/Bozozok-independent induction of the dorsal organizer by zebrafish cell lines.

Developmental biology - 15 Sept 2008

Hashiguchi Megumi, Shinya Minori, Tokumoto Mika, Sakai Noriyoshi

Abstract excerpt

Formation of the dorsal organizer (Spemann organizer) is an important process in early vertebrate development. In zebrafish, two molecular cascades--Bozozok/Dharma (Boz) and Nodal signaling--act in parallel to induce the dorsal organizer. However, the complete molecular mechanism regulating this event remains unclear. Here we report that zebrafish cell lines derived from various developmental stages can induce a...

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PMID: 18652819
DOI: 10.1016/j.ydbio.2008.06.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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