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Article

Ebola virus transcription activator VP30 is a zinc-binding protein.

Journal of virology - 1 Mar 2003

Modrof Jens, Becker Stephan, Mühlberger Elke

Abstract excerpt

Ebola virus VP30 is an essential activator of viral transcription. In viral particles, VP30 is closely associated with the nucleocapsid complex. A conspicuous structural feature of VP30 is an unconventional zinc-binding Cys(3)-His motif comprising amino acids 68 to 95. By using a colorimetric zinc-binding assay we found that the VP30-specific Cys(3)-His motif stoichiometrically binds zinc ions in a one-to-one...

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Identifiers

PMID: 12584359
DOI: 10.1128/jvi.77.5.3334-3338.2003
PMCID: PMC149768

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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