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Article

Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas

1 Feb 2003

Abstract excerpt

To understand the role of gene promoter methylation in neoplastic evolution and progression, the methylation changes associated with 15 candidate tumor suppressor genes were studied throughout stages of tumor progression involving intraductal papillary mucinous neoplasms (IPMN) of the pancreas. Genomic DNA from 28 pancreatic IPMN tissue samples, categorized histologically as non-invasive intraductal IPMN (n = 3),...

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Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation
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PMID: 12584167
DOI: 10.1093/carcin/24.2.193

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