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Article

Exoneration of NF-kappaB dysregulation in fibrodysplasia ossificans progressiva.

Clinical orthopaedics and related research - 1 Jan 2003

Ahn Jaimo, Feldman George, Terry Leota, Shore Eileen M, Kaplan Frederick S

Abstract excerpt

Fibrodysplasia ossificans progressiva is a disabling genetic disorder characterized by congenital skeletal malformations and progressive heterotopic ossification. New episodes of ossification are heralded by preosseous inflammatory lesions replete with B and T lymphocytes that overexpress bone morphogenetic protein-4. NF-kappaB is an inflammatory mediator that plays a critical role in developmental skeletogenesis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12579020
DOI: 10.1097/01.blo.0000030075.92399.11

Genes

NFKB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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