Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PARESIS OF A BONE MORPHOGENETIC PROTEIN-ANTAGONIST RESPONSE IN A GENETIC DISORDER OF HETEROTOPIC SKELETOGENESIS

1 Apr 2003

Abstract excerpt

BACKGROUND: Fibrodysplasia ossificans progressiva is a rare genetic disorder characterized by congenital malformations of the great toes and by progressive heterotopic bone formation. Bone morphogenetic protein-4 (BMP-4) messenger ribonucleic acid (mRNA) and protein are uniquely overexpressed in lymphocytes and lesional cells from patients who have fibrodysplasia ossificans progressiva. However, the BMP-4 gene is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Kidney Cyst Diseases
Share to Heterotopic Ossification and Related Conditions
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12672843
DOI: 10.2106/00004623-200304000-00013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PARESIS OF A BONE MORPHOGENETIC PROTEIN-ANTAGONIST RESPONSE IN A GENETIC DISORDER OF HETEROTOPIC SKELETOGENESISPMID 12672843Read ↗

Overexpression of an Osteogenic Morphogen in Fibrodysplasia Ossificans ProgressivaSemantic proximity Read ↗

Dysregulation of the BMP‐4 Signaling Pathway in Fibrodysplasia Ossificans ProgressivaSemantic proximity Read ↗

Fibrodysplasia Ossificans Progressiva (FOP), a Disorder of Ectopic Osteogenesis, Misregulates Cell Surface Expression and Trafficking of BMPRIASemantic proximity Read ↗

Dysregulation of the BMP-p38 MAPK Signaling Pathway in Cells From Patients With Fibrodysplasia Ossificans Progressiva (FOP)Semantic proximity Read ↗

Encrypted morphogens of skeletogenesis: biological errors and pharmacologic potentials.Semantic proximity Read ↗

Deregulated bone morphogenetic protein receptor signaling underlies fibrodysplasia ossificans progressiva.Semantic proximity Read ↗

Phenotypic and molecular heterogeneity in fibrodysplasia ossificans progressiva.Semantic proximity Read ↗

Hematopoietic Stem-Cell Contribution to Ectopic SkeletogenesisSemantic proximity Read ↗

Hematopoietic Stem-Cell Contribution to Ectopic SkeletogenesisSemantic proximity Read ↗

Exoneration of NF-kappaB dysregulation in fibrodysplasia ossificans progressiva.Semantic proximity Read ↗

IN VIVO SOMATIC CELL GENE TRANSFER OF AN ENGINEERED NOGGIN MUTEIN PREVENTS BMP4-INDUCED HETEROTOPIC OSSIFICATIONSemantic proximity Read ↗

Dynamics of BMP signaling in limb bud mesenchyme and polydactyly.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.