Article
[Pathophysiologic aspects of endothelial NO-synthase genetic polymorphism].
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) - 1 Jan 2002
Dosenko V Ie, Zahoriĭ V Iu, Moĭbenko O O, Parkhomenko O M
Abstract excerpt
Information about fourteen allelic variants of promoter, exons and introns of a gene of endothelial NO-synhase (eNOS) dealing with their role in a susceptibility to cardio-vascular diseases has been reviewed. Data of the populational genetic studies, performed in different regions of the world, were analysed to show the interrelation between an availability of on allele in the genome and a risk of ischemic heart...
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