Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of antigenic epitopes on human allergens: studies with HLA transgenic mice.

Environmental health perspectives - 1 Feb 2003

Chapoval Svetlana P, David Chella S

Abstract excerpt

Environmental factors play an important role in the rise and manifestation of allergic conditions in genetically predisposed subjects. Increased exposure to indoor/outdoor allergens is a significant factor in the development of allergic sensitization and asthma. Recently, strong relationships between the immune response to several highly purified allergens and specific human leukocyte antigen (HLA)-DQ and -DR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allergens
Share to Asthma
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitopes

Share to HLA-DQ Antigens

Share to HLA-DR Antigens

Share to Mice, Transgenic

Source

Open in PubMed Open full text

Identifiers

PMID: 12573914
DOI: 10.1289/ehp.5706
PMCID: PMC1241359

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of antigenic epitopes on human allergens: studies with HLA transgenic mice.PMID 12573914Read ↗

HLA class II transgenic mice as models of human diseasesSemantic proximity Read ↗

The use of human leucocyte antigen class I transgenic mice to investigate human immune function.Semantic proximity Read ↗

Application of Humanized MHC Transgenic Mice in the Screening of HLA–Restricted T Cell Epitopes for Influenza VaccinesSemantic proximity Read ↗

HLA class II polymorphism influences the immune response to protective antigen and susceptibility to <i>Bacillus anthracis</i>Semantic proximity Read ↗

HLA transgenic mice as humanized mouse models of disease and immunity.Semantic proximity Read ↗

House dust mite allergen characterisation: implications for T-cell responses and immunotherapy.Semantic proximity Read ↗

Development of a humanized HLA‐A30 transgenic mouse modelSemantic proximity Read ↗

Transgenic mice expressing the T cell antigen receptor specific for an immunodominant epitope of a major allergen of house dust mite develop an asthmatic phenotype on exposure of the airways to allergen.Semantic proximity Read ↗

Determinants of allergenicity.Semantic proximity Read ↗

Transgenic mice which overproduce Th2 cytokines develop spontaneous atopic dermatitis and asthmaSemantic proximity Read ↗

HLA-DRB1 alleles control allergic bronchopulmonary aspergillosis-like pulmonary responses in humanized transgenic mice.Semantic proximity Read ↗

Hyper-reactive cloned mice generated by direct nuclear transfer of antigen-specific CD4+ T cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.